Clinical results suggest a minimum use of four months before hair growth can be expected. Topical application of Minoxidil showed no systemic effect in the prescribed dosage i.e. 2 (two) applications per day.
PROPERTIES:Minoxin (Minoxidil Topical Solution USP) stimulates hair growth in individuals with androgenetic alopecia expressed as baldness of the vertex of the scalp in males and in females as diffuse hair loss or thinning of frontoparietal areas. Clinical results suggest a minimum use of four months before hair growth can be expected. Topical application of Minoxidil showed no systemic effect in the prescribed dosage i.e. 2 (two) applications per day
PHARMACOKINETICS:On topical application minoxidil is poorly absorbed, from normal intact scalp with an average of 1.4 % (0.3 to 4.5 %) of the total applied dose, reaching systemic circulation. Therefore, 1 (one) ml of Minoxidil 2 % delivering 20 mg Minoxidil and Minoxidil 5 % delivering 50 mg Minoxidil to the skin, would result in absorption of approximately 0.280 mg of Minoxidil 2% and 0.700 mg of Minoxidil 5% respectively. Local abrasion or dermatitis may enhance absorption. Serum Minoxidil levels resulting from topical administration are governed by the drugs percutaneous absorption rate. Following cessation of topical dosing approximately 95% of systemically absorbed Minoxidil is eliminated within 4 days. Metabolic biotransformation of Minoxidil absorbed following topical application has not been fully determined.INDICATIONS AND USAGE:Minoxin (Minoxidil Topical Solution USP) is indicated for treatment of androgenetic alopecia, expressed in males as baldness of the vertex of the scalp and in females as diffuse hair loss or thinning of frontoparietal area. At least, 4 (four) months of twice daily application of Minoxin (Minoxidil Topical Solution USP) are generally required before evidence of hair growth can be expectedFOR MORE INFOMINOXIN